Using a rechargeable portable vacuum cleaner to clean a PCIe 16x slot on your motherboard should generally be safe, as long as you take some precautions and use the vacuum properly. However, it's important to be cautious and follow these guidelines to minimize any potential risks:
Ensure the PC is powered off and unplugged: Before attempting to clean any components inside your computer, always turn off the PC, unplug it from the power source, and discharge any static electricity from your body by touching a grounded metal surface.
Use a low-powered vacuum or blower: If you're using a vacuum cleaner, make sure it's a low-powered model or set it to a low suction level. High-powered vacuum cleaners can generate static electricity and may cause damage to sensitive electronic components.
Anti-static precautions: Static electricity can be harmful to computer components. To minimize the risk of static discharge, use an anti-static wrist strap or regularly touch a grounded metal surface (like the metal part of your PC case) while cleaning.
Hold the vacuum nozzle slightly above the PCIe slot: Avoid inserting the vacuum nozzle directly into the slot to prevent any accidental damage to the slot or its contacts.
Gentle cleaning: Be gentle while cleaning, and don't apply excessive force to avoid bending or damaging the PCIe slot or any nearby components.
Consider using compressed air: Instead of a vacuum cleaner, you may also use compressed air in a can (also known as "canned air") to blow away dust and debris from the PCIe slot. Make sure the can is held upright during use to avoid any moisture from being sprayed onto the components.
Inspect the slot afterward: Once you've cleaned the PCIe slot, inspect it carefully to ensure there are no visible signs of damage or any foreign objects remaining inside.
If you followed these precautions and were gentle during the cleaning process, the risk of causing any harm to your motherboard or PCIe slot should be minimal. However, it's always a good idea to double-check everything and perhaps run some basic tests on your computer after cleaning to ensure all components are functioning as expected. If you have any doubts or concerns about the cleaning process, consider seeking help from a professional technician.