No, you should not make a panini in a regular toaster. A panini is a type of sandwich that is traditionally grilled or pressed, typically with specialized equipment designed for this purpose. While toaster ovens may have a "panini" setting or a grill function, using a regular pop-up toaster for making a panini is not recommended and can be dangerous.
Toasters are designed to toast bread slices using a heating element inside a confined space. Placing a panini or any other sandwich with fillings inside a regular toaster can cause the fillings to melt, leak, or even catch fire due to the proximity of the heating elements and the lack of space for proper ventilation.
If you want to make a panini at home, consider using a panini press, a stovetop grill pan, or a sandwich maker specifically designed for this purpose. These appliances provide even heating and pressure, ensuring your panini turns out delicious without any risk of accidents.